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PubMed Central is a free full-text archive of biomedical and life sciences journal literature at the U.S. National Institutes of Health's National Library of Medicine (NIH/NLM).


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by Roncero, Carlos; Vega, Pablo; Martinez-Raga, Jose; Barral, Carmen; Basurte-Villamor, Ignacio; Rodriguez-Cintas, Laia; Mesias, Beatriz; Grau-Lopez, Lara; Casas, Miguel; Szerman, Nestor
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This article is from International Journal of Mental Health Systems , volume 8 . Abstract Background: Since provision of integrated services for patients with dual pathology or dual disorders (coexistence of an addictive disorder and other psychiatric disorders) constitutes an important challenge, this study compared the perceptions of health-care professionals with the existing, current state of specific resources for patients with dual pathology in Spain. Methods: Epidemiological,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158069
PubMed Central
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This article is from Iranian Journal of Psychiatry and Behavioral Sciences , volume 6 . Abstract Objective: Approximately 66-80%of graduate students experience statistics anxiety and some researchers propose that many students identify statistics courses as the most anxiety-inducing courses in their academic curriculums. As such, it is likely that statistics anxiety is, in part, responsible for many students delaying enrollment in these courses for as long as possible. This paper proposes a...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939948
PubMed Central
by de Visser, Sam P.
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This article is from Frontiers in Chemistry , volume 1 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982559
PubMed Central
by Williams, Antony J
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This article is from Journal of Cheminformatics , volume 4 . Abstract The International Chemical Identifier (InChI) has had a dramatic impact on providing a means by which to deduplicate, validate and link together chemical compounds and related information across databases. Its influence has been especially valuable as the internet has exploded in terms of the amount of chemistry related information available online. This thematic issue aggregates a number of contributions demonstrating the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537679
PubMed Central
by Koszytkowska-Stawinska, Mariola; Buchowicz, Wlodzimierz
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This article is from Beilstein Journal of Organic Chemistry , volume 10 . Abstract This review covers sixty original publications dealing with the application of multicomponent reactions (MCRs) in the synthesis of novel nucleoside analogs. The reported approaches were employed for modifications of the parent nucleoside core or for de novo construction of a nucleoside scaffold from non-nucleoside substrates. The cited references are grouped according to the usually recognized types of the MCRs....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142899
PubMed Central
by Suib, Steven L.
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This article is from Frontiers in Chemistry , volume 1 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982573
PubMed Central
by Qiu, Ling; Cheng, Xin-qi; Wu, Jie; Liu, Jun-ting; Xu, Tao; Ding, Hai-tao; Liu, Yan-hong; Ge, Zeng-mei; Wang, Ya-jing; Han, Hui-juan; Liu, Jing; Zhu, Guang-jin
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This article is from BMC Public Health , volume 13 . Abstract Background: Hyperuricemia (HUA) is a potential risk factor for developing insulin resistance, hypertension, dyslipidemia and cardiovascular disease. Therefore, we studied the prevalence of HUA and associated risk factors in the population of two provinces in northern China. Methods: Based on the research of Chinese Physiological Constant and Health Conditions conducted in 2008–2010, we enrolled 29,639 subjects in a randomized,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722003
PubMed Central
by Sherrington, David
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This article is from Philosophical transactions. Series A, Mathematical, physical, and engineering sciences , volume 368 . Abstract This paper is concerned with complex macroscopic behaviour arising in many-body systems through the combinations of competitive interactions and disorder, even with simple ingredients at the microscopic level. It attempts to indicate and illustrate the richness that has arisen, in conceptual understanding, in methodology and in application, across a large range of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263799
PubMed Central
by Foote, Christopher
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This article is from BMC Research Notes , volume 7 . Abstract Contributing reviewers: The editors of BMC Research Notes would like to thank all of our reviewers who have contributed to the journal in volume 6 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895785
PubMed Central
by Rice, Catherine M
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This article is from BMC Genomics , volume 14 . Abstract Contributing reviewers: The editors of BMC Genomics would like to thank all our reviewers who have contributed to the journal in volume 13 (2012).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642022
PubMed Central
by DiSilvestro, Robert A; Joseph, Elizabeth; Zhao, Shi; Bomser, Joshua
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This article is from Nutrition Journal , volume 11 . Abstract Background: Curcumin extracts of turmeric are proposed to produce health benefits. To date, human intervention studies have focused mainly on people with existing health problems given high doses of poorly absorbed curcumin. The purpose of the current study was to check whether in healthy people, a low dose of a lipidated curcumin extract could alter wellness-related measures. Methods: The present study was conducted in healthy...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518252
PubMed Central
by Morawska, Magdalena
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This article is from BMC Gastroenterology , volume 14 . Abstract Contributing reviewers: The editors of BMC Gastroenterology would like to thank all of our reviewers who have contributed to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898228
PubMed Central
by Axelsson, Martin; Gentili, Francesco
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This article is from PLoS ONE , volume 9 . Abstract Microalgae produce a wide range of lipid compounds of potential commercial interest. Total lipid extraction performed by conventional extraction methods, relying on the chloroform-methanol solvent system are too laborious and time consuming for screening large numbers of samples. In this study, three previous extraction methods devised by Folch et al. (1957), Bligh and Dyer (1959) and Selstam and Öquist (1985) were compared and a faster...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933640
PubMed Central
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This article is from Journal of Diabetes and Metabolic Disorders , volume 12 . Abstract Background: Obesity (abdominal adiposity) is a risk factor for cardiovascular diseases and the most used methods to measure the adiposity are body mass index (BMI), waist circumference (WC), and sagittal abdominal diameter (SAD). Objective: To correlate BMI, WC, and SAD with biochemical parameters and blood pressure in adults. Methods: A non-experimental exploratory/descriptive and cross sectional study was...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733622
PubMed Central
by Kelly, John J.; Minalt, Nicole; Culotti, Alessandro; Pryor, Marsha; Packman, Aaron
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This article is from PLoS ONE , volume 9 . Abstract Pipes that transport drinking water through municipal drinking water distribution systems (DWDS) are challenging habitats for microorganisms. Distribution networks are dark, oligotrophic and contain disinfectants; yet microbes frequently form biofilms attached to interior surfaces of DWDS pipes. Relatively little is known about the species composition and ecology of these biofilms due to challenges associated with sample acquisition from...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032344
PubMed Central
by Teisala, Tiina; Mutikainen, Sara; Tolvanen, Asko; Rottensteiner, Mirva; Leskinen, Tuija; Kaprio, Jaakko; Kolehmainen, Marjukka; Rusko, Heikki; Kujala, Urho M
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This article is from Journal of Occupational Medicine and Toxicology (London, England) , volume 9 . Abstract Background: The purpose of this study was to investigate how physical activity (PA), cardiorespiratory fitness (CRF), and body composition are associated with heart rate variability (HRV)-based indicators of stress and recovery on workdays. Additionally, we evaluated the association of objectively measured stress with self-reported burnout symptoms. Methods: Participants of this...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997193
PubMed Central
by Kim, Hee-Yun; Lee, Hee-Won; Jung, Seung-Ho; Kang, Min-Hee; Bae, Jae-Nam; Lee, Jeong-Seop; Kim, Chul-Eung
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This article is from Clinical Psychopharmacology and Neuroscience , volume 12 . Abstract Objective: This study investigated the prescription patterns for Korean patients with schizophrenia with a particular focus on antipsychotic polypharmacy. All data were gathered from patients presenting at 41 tertiary university hospitals and 8 secondary hospitals. Methods: Data from three multicenter studies conducted in Korea were retrospectively reviewed and integrated to identify patients with...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153859
PubMed Central
by Pan, Sun; Wu, Duojiao; Teschendorff, Andrew E.; Hong, Tao; Wang, Linyan; Qian, Mengjia; Wang, Chunsheng; Wang, Xiangdong
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This article is from PLoS ONE , volume 9 . Abstract The precise mechanisms underlying dissections, especially those without connective tissue diseases or congenital vascular diseases, are incompletely understood. This study attempted to identify both the expression profile of the dissected ascending aorta and the interactome hotspots associated with the disease, using microarray technology and gene regulatory network analysis. There were 2,737 genes differentially expressed between patients...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933461
PubMed Central
by Hommel, Marcel
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This article is from Malaria Journal , volume 13 . Abstract Contributing reviewers: Malaria Journal would like to thank all reviewers who have contributed to the journal in 2013.
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917501
PubMed Central
by Ho, Mandy; Gow, Megan; Halim, Jocelyn; Chisholm, Kerryn; Baur, Louise A; Noakes, Manny; Steinbeck, Katherine; Kohn, Michael R; Cowell, Chris T; Garnett, Sarah P
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This article is from The International Journal of Behavioral Nutrition and Physical Activity , volume 10 . Abstract Background: Overweight adolescents are more likely to have dysfunctional eating behaviours compared to normal weight adolescents. Little is known about the effects of obesity treatment on the psychological dimensions of eating behavior in this population. Objective: To examine the effects of a prescriptive dietary intervention on external eating (eating in response to food cues,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842818
PubMed Central
by Harold, Simon
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This article is from BMC Plant Biology , volume 14 . Abstract Contributing reviewers: The editors of BMC Plant Biology would like to thank all of our reviewers who have contributed to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897928
PubMed Central
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This article is from Virology Journal , volume 11 . Abstract : The editors of Virology Journal would like to thank all our reviewers who have contributed to the journal in Volume 10 (2013). The success of any scientific journal depends on an effective and strict peer review process and Virology Journal could not operate without your contribution. We are grateful to the large number of reviewers (1026 to be exact!), who have done a great job in not only lifting the quality of the journal’s...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898089
PubMed Central
by Moini Zanjani, Taraneh; Ameli, Haleh; Labibi, Farzaneh; Sedaghat, Katayoun; Sabetkasaei, Masoumeh
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This article is from The Korean Journal of Pain , volume 27 . Abstract Background: Neuropathic pain is generally defined as a chronic pain state resulting from peripheral and/or central nerve injury. There is a lack of effective treatment for neuropathic pain, which may possibly be related to poor understanding of pathological mechanisms at the molecular level. Curcumin, a therapeutic herbal extract, has shown to be effectively capable of reducing chronic pain induced by peripheral...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099237
PubMed Central
by Doran, Tim; Kontopantelis, Evangelos; Valderas, Jose M; Campbell, Stephen; Roland, Martin; Salisbury, Chris; Reeves, David
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This article is from BMJ : British Medical Journal , volume 342 . Abstract Objective To investigate whether the incentive scheme for UK general practitioners led them to neglect activities not included in the scheme.Design Longitudinal analysis of achievement rates for 42 activities (23 included in incentive scheme, 19 not included) selected from 428 identified indicators of quality of care.Setting 148 general practices in England (653 500 patients).Main outcome measures Achievement rates...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125475
PubMed Central
by Fu, Weihua; Zhou, Zhansong; Liu, Shijian; Li, Qianwei; Yao, Jiwei; Li, Weibing; Yan, Junan
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This article is from PLoS ONE , volume 9 . Abstract Background: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is one of the risk factors of impaired male fertility potential. Studies have investigated the effect of CP/CPPS on several semen parameters but have shown inconsistent results. Hence, we performed a systematic literature review and meta-analysis to assess the association between CP/CPPS and basic semen parameters in adult men. Methods: Systematic literature searches were...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990624
PubMed Central
by Veening, Jan G; Gerrits, Peter O; Barendregt, Henk P
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This article is from Fluids and Barriers of the CNS , volume 9 . Abstract There is increasing evidence that non-synaptic communication by volume transmission in the flowing CSF plays an important role in neural mechanisms, especially for extending the duration of behavioral effects. In the present review, we explore the mechanisms involved in the behavioral and physiological effects of β-endorphin (β-END), especially those involving the cerebrospinal fluid (CSF), as a message transport system...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439317
PubMed Central
by Solera, Dafne
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This article is from BMC Cancer , volume 14 . Abstract Contributing reviewers: The editors of BMC Cancer would like to thank all our reviewers who have contributed to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909450
PubMed Central
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This article is from Frontiers in Human Neuroscience , volume 8 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125967
PubMed Central
by Harold, Simon
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This article is from BMC Plant Biology , volume 13 . Abstract Contributing reviewers: The editors of BMC Plant Biology would like to thank all of our reviewers who have contributed to the journal in Volume 12 (2012).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576327
PubMed Central
by Pafitis, Natalie
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This article is from BMC Public Health , volume 13 . Abstract Contributing reviewers: The editors of BMC Public Health would like to thank all our reviewers who have contributed to the journal in 2012.
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751667
PubMed Central
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This article is from Critical Care , volume 18 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068645
PubMed Central
by Nair, Pragya A; Chaudhary, Arvind H; Mehta, Malay J
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This article is from ecancermedicalscience , volume 7 . Abstract Cutaneous horns are usually found on chronic sun-damaged skin. A cutaneous horn is a rare tumour, often conical, circumscribed, and composed of dead keratin usually derived from base keratinocytes. It occurs mainly in association with underlying benign, premalignant, and malignant cutaneous diseases. The commonest malignancy is squamous cell carcinoma. Thus, to accurately ascertain the nature of the condition at the base of the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842183
PubMed Central
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This article is from Avicenna Journal of Phytomedicine , volume 3 . Abstract Objective: Several phytochemical agents have been known to exhibit a neuroprotective effect. Among them, curcumin, linalool, rutin, safranal, and thymoquinone were widely investigated and neuroprotective activity of each of them was shown by several studies. This work was planned to investigate whether different combinations of them could induce better neuroprotective effect against glucose/serum deprivation...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075728
PubMed Central
by Lindoso, Jose Angelo; Cota, Glaucia Fernandes; da Cruz, Alda Maria; Goto, Hiro; Maia-Elkhoury, Ana Nilce Silveira; Romero, Gustavo Adolfo Sierra; de Sousa-Gomes, Marcia Leite; Santos-Oliveira, Joanna Reis; Rabello, Ana
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This article is from PLoS Neglected Tropical Diseases , volume 8 . Abstract Visceral leishmaniasis (VL) is an endemic zoonotic disease in Latin America caused by Leishmania (Leishmania) infantum, which is transmitted by sand flies from the genus Lutzomyia. VL occurs in 12 countries of Latin America, with 96% of cases reported in Brazil. Recently, an increase in VL, primarily affecting children and young adults, has been observed in urban areas of Latin America. The area in which this spread of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169383
PubMed Central
by Li, Lei; Huang, Dandan; Cheung, Man Kit; Nong, Wenyan; Huang, Qianli; Kwan, Hoi Shan
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This article is from Nucleic Acids Research , volume 41 . Abstract In bacteria, small regulatory non-coding RNAs (sRNAs) are the most abundant class of post-transcriptional regulators. They are involved in diverse processes including quorum sensing, stress response, virulence and carbon metabolism. Recent developments in high-throughput techniques, such as genomic tiling arrays and RNA-Seq, have allowed efficient detection and characterization of bacterial sRNAs. However, a comprehensive...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531160
PubMed Central
by Kim, Jinseog; Sohn, Insuk; Son, Dae-Soon; Kim, Dong Hwan; Ahn, Taejin; Jung, Sin-Ho
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This article is from BMC Bioinformatics , volume 14 . Abstract Background: A popular objective of many high-throughput genome projects is to discover various genomic markers associated with traits and develop statistical models to predict traits of future patients based on marker values. Results: In this paper, we present a prediction method for time-to-event traits using genome-wide single-nucleotide polymorphisms (SNPs). We also propose a MaxTest associating between a time-to-event trait and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651372
PubMed Central
by Majithia, Deesha A
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This article is from BMC Neuroscience , volume 14 . Abstract Contributing reviewers: The editors of BMC Neuroscience would like to thank all our reviewers who have contributed to the journal in Volume 13 (2012).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626905
PubMed Central
by Lossius, Hans Morten; S?reide, Kjetil; Bache, Kristi G
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This article is from Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine , volume 22 . Abstract Contributing reviewers: The Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine—which received its first Impact Factor in 2013—is extremely grateful for the time, hard work and support of its highly-qualified peer reviewers. The editors of the Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, the Norwegian Air Ambulance Foundation and BioMed...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973829
PubMed Central
by Rowles, Thomas A
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This article is from BMC Surgery , volume 14 . Abstract Contributing reviewers: The editors of BMC Surgery would like to thank all our reviewers who have contributed their time to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893518
PubMed Central
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This article is from Annals of The Royal College of Surgeons of England , volume 94 . Abstract INTRODUCTION: The preliminary results of a pyrocarbon interpositional radiocarpal implant in a small cohort of patients were reviewed. As it is currently only a limited release product, we describe to potential users early complications and negative outcomes. METHODS: Patients were assessed using pain levels, ranges of motion, grip strength, type of and time to return to work as well as pre-operative...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954246
PubMed Central
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This article is from Pakistan Journal of Medical Sciences , volume 30 . Abstract Objective: The rate of recurrence in high grade non muscle invasive bladder cancer (NMIBC) is 70% with progression rate of 15-40% at 5 years. The treatment of high grade NMIBC is intravesical BCG therapy, however for high risk cases radical cystectomy is recommended. In this study we determined the response of high grade NMIBC to BCG therapy and the factors affecting it in south Asian population.Methods: This...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999003
PubMed Central
by Kinoshita, Hiroyuki; Sakata, Yoshifumi; Umano, Yasukazu; Iwamoto, Hiromitsu; Mori, Kazunari
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This article is from World Journal of Surgical Oncology , volume 12 . Abstract Background: Wide margins of resection and regional lymphadenectomy for GIST are not necessary. Several procedures for rectal GIST have been designed according to the location and size of the tumor to preserve the anal function and decrease the morbidity rate. Case presentation: We report a 61-year-old-man with rectal bleeding. Proctologic examination revealed a small mass of approximately 2 cm in diameter on the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987675
PubMed Central
by Shipley, Tim
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This article is from BMC Neurology , volume 14 . Abstract Contributing reviewers: The editors of BMC Neurology would like to thank all our reviewers who have contributed to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973960
PubMed Central
by Morawska, Magdalena
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This article is from BMC Oral Health , volume 14 . Abstract Contributing reviewers: The editors of BMC Oral Health would like to thank all of our reviewers who have contributed to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921989
PubMed Central
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This article is from BMC Evolutionary Biology , volume 14 . Abstract Background: Pathogens are a major regulatory force for host populations, especially under stressful conditions. Elevated temperatures may enhance the development of pathogens, increase the number of transmission stages, and can negatively influence host susceptibility depending on host thermal tolerance. As a net result, this can lead to a higher prevalence of epidemics during summer months. These conditions also apply to...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115170
PubMed Central
by Wijnants, Maarten L.; Cox, R. F. A.; Hasselman, F.; Bosman, A. M. T.; Van Orden, Guy
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This article is from Frontiers in Physiology , volume 3 . Abstract Spectral analysis is a widely used method to estimate 1/fα noise in behavioral and physiological data series. The aim of this paper is to achieve a more solid appreciation for the effects of periodic sampling on the outcomes of spectral analysis. It is shown that spectral analysis is biased by the choice of sample rate because denser sampling comes with lower amplitude fluctuations at the highest frequencies. Here we introduce...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549522
PubMed Central
by Harris, Philippa K
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This article is from BMC Microbiology , volume 13 . Abstract Contributing reviewers: The editors of BMC Microbiology would like to thank all our reviewers who have contributed to the journal in Volume 12 (2012).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576289
PubMed Central
by Zhao, Qingqing; Li, Qunhui; Zhong, Lei; Gu, Min; Zhu, Jie; Zhao, Guo; Chen, Chaoyang; Wang, Xiaoquan; Liu, Xiaowen; Liu, Xiufan
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This article is from Genome Announcements , volume 1 . Abstract Here, we report the complete genomic sequence of a novel reassortant H4N2 influenza virus isolated from domestic ducks in the Jiangsu province of China in 2011. Phylogenetic analysis showed that all the viral genes except for hemagglutinin (HA) were highly homologous to the clade 2.3.4 H5N2 viruses. The data suggest that genetic reassortment occurred between H4 and H5N2 avian influenza viruses, which highlights the role of domestic...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622964
PubMed Central
by Razafimanantsoa, Fetralinjiva; Razafindramaro, Notahiana; Raherimandimby, Hasina; Robinson, Annick; RakotoAlson, Olivat; Rasamindrakotroka, Andry
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This article is from The Pan African Medical Journal , volume 16 . Abstract Les enfants tananariviens sont en état de malnutrition chronique. Notre objectif est d’évaluer l'indice de masse corporelle (IMC) pour estimer les enfants apparemment "sains". Une enquête et une mesure de la taille et du poids des enfants scolarisés tananariviens de 6 à 11 ans ont été réalisées. Après leur accord, la taille et l'indice de masse corporelle des 442 enfants tirés au hasard ont été...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976650
PubMed Central
by Jeon, Younghoon; Kim, Chae-Eun; Jung, Dongho; Kwak, Kyunghwa; Park, Sungsik; Lim, Donggun; Kim, Sioh; Baek, Woonyi
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This article is from Current Therapeutic Research, Clinical and Experimental , volume 74 . Abstract Background: Peripheral nerve injury results in chronic neuropathic pain characterized by allodynia and/or spontaneous pain. It has been suggested that activation of mitogen-activated protein kinases such as extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) contribute to the neuropathic pain. Objectives: We investigated if curcumin could prevent the development of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862204
PubMed Central
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This article is from Biomolecules , volume 4 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030993
PubMed Central
by Salesi, Mansour; Mottaghi, Peyman; Karimifar, Mansour; Farajzadegan, Ziba
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This article is from Journal of Research in Medical Sciences : The Official Journal of Isfahan University of Medical Sciences , volume 17 . Abstract Background:: Patients with rheumatoid arthritis may be resistant to conventional treatment with disease-modifying antirheumatic drugs (DMARDs). On the other hand, biologic therapy is costly and may be inconvenient for many patients. Pamidronate is a potent bisphosphonate with the capacity of modifying the biological activity of the immune system...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634265
PubMed Central
by Rettinger, Eva; Glatthaar, Andreas; Abhari, Behnaz Ahangarian; Oelsner, Sarah; Pfirrmann, Verena; Huenecke, Sabine; Kuci, Selim; Kreyenberg, Hermann; Willasch, Andre M.; Klingebiel, Thomas; Fulda, Simone; Bader, Peter
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This article is from Frontiers in Pediatrics , volume 2 . Abstract Allogeneic hematopoietic stem cell transplantation (HSCT) is an established treatment option for high-risk hematological malignancies, and may also be offered to patients with solid malignancies refractory to conventional therapies. In case of patients’ relapse, refractory tumor cells may then be targeted by cellular therapy-based combination strategies. Here, we investigated the potential of small molecule IAP (SMAC mimetic)...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103003
PubMed Central
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This article is from BMJ Open , volume 4 . Abstract Objectives: To test the effects of a school-based prevention programme on students’ smoking-related behaviour, attitudes and knowledge 6 months after implementation over 2 school-years has ended. Design: Two-arm prospective cluster randomised controlled trial with a follow-up survey 6 months after end of programme implementation, that is, 26 months after baseline. Setting: 45 public secondary schools from four federal states in Germany...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902526
PubMed Central
by Chan, Micah R; Ghandour, Fadi; Murali, Narayana S.; Washburn, MJ; Astor, Brad C.
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This article is from Journal of nephrology & therapeutics , volume 4 . Abstract Background: Currently there is a lack of effective treatment options for patients with calciphylaxis. There is anecdotal evidence that non-calcium based phosphorus binders may offer some benefit. The aim of this pilot study is to determine if lanthanum carbonate is effective in inducing remission of calciphylaxis lesions and demonstrate an improved DLQI (Dermatology Life Quality Index). Methods: This is a...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170220
PubMed Central
by Casadevall, Arturo
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This article is from mBio , volume 5 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128361
PubMed Central
by Romao, Susana; Gasser, Nathalie; Becker, Andrea C.; Guhl, Bruno; Bajagic, Milica; Vanoaica, Danusia; Ziegler, Urs; Roesler, Joachim; Dengjel, Jorn; Reichenbach, Janine; Munz, Christian
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This article is from The Journal of Cell Biology , volume 203 . Abstract A subset of phagosomes in human macrophages and dendritic cells that is marked by a coat of autophagy-related proteins maintains phagocytosed antigens for prolonged presentation on MHC class II molecules.
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857489
PubMed Central
by Ponader, Daniela; Igde, Sinaida; Wehle, Marko; Marker, Katharina; Santer, Mark; Bleger, David; Hartmann, Laura
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This article is from Beilstein Journal of Organic Chemistry , volume 10 . Abstract The synthesis of photoswitchable glycooligomers is presented by applying solid-phase polymer synthesis and functional building blocks. The obtained glycoligands are monodisperse and present azobenzene moieties as well as sugar ligands at defined positions within the oligomeric backbone and side chains, respectively. We show that the combination of molecular precision together with the photoswitchable properties...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143111
PubMed Central
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This article is from United European Gastroenterology Journal , volume 1 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070603
PubMed Central
by Niederalt, Christoph; Wendl, Thomas; Kuepfer, Lars; Claassen, Karina; Loosen, Roland; Willmann, Stefan; Lippert, Joerg; Schultze-Mosgau, Marcus; Winkler, Julia; Burghaus, Rolf; Brautigam, Matthias; Pietsch, Hubertus; Lengsfeld, Philipp
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eye 179
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This article is from Frontiers in Physiology , volume 3 . Abstract A physiologically based kidney model was developed to analyze the renal excretion and kidney exposure of hydrophilic agents, in particular contrast media, in rats. In order to study the influence of osmolality and viscosity changes, the model mechanistically represents urine concentration by water reabsorption in different segments of kidney tubules and viscosity dependent tubular fluid flow. The model was established using...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553339
PubMed Central
by Rostamzadeh, Ayoob; Mirfendereski, Sam; Rezaie, Mohammad Jafar; Rezaei, Shohreh
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This article is from Pakistan Journal of Medical Sciences , volume 30 . Abstract Objectives: Misdiagnosing ovarian torsion is now suggested as an important issue in clinical setting. The aim of this study was to determine the diagnostic accuracy of sonography for ovarian torsion.Methods: In this study 323 women with acute pelvic pain with highly suspected ovarian torsion signs and symptoms attending Imam Reza Medical Center in Kermanshah between 2011 through 2012 were included and underwent a...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999021
PubMed Central
by Badgaiyan, Rajendra D.
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This article is from Frontiers in Neuroscience , volume 7 . Abstract Current imaging techniques have limited ability to detect neurotransmitters released during brain processing. It is a critical limitation because neurotransmitters have significant control over the brain activity. In this context, recent development of single-scan dynamic molecular imaging technique is important because it allows detection, mapping, and measurement of dopamine released in the brain during task performance. The...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714787
PubMed Central
by Ahmadi, Arezoo; Ardehali, Seyed Hossein; Beigmohammadi, Mohammad Taghi; Hajiabdolbaghi, Mahboubeh; Hashemian, Seyed Mohammad Reza; Kouchek, Mehran; Majidpour, Ali; Mokhtari, Majid; Moghaddam, Omid Moradi; Najafi, Atabak; Nejat, Reza; Niakan, Mohammad; Lotfi, Amir Hossein; Amirsavadkouhi, Ali; Shirazian, Farzad; Tabarsi, Payam; Taher, Mahshid Talebi; Torabi-Nami, Mohammad
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This article is from JRSM Open , volume 5 . Abstract Invasive candidiasis (IC) is associated with high mortality in intensive care unit (ICU) patients. Timely diagnosis of this potentially fatal condition remains a challenge; on the other hand, the criteria for initiating empirical antifungal therapy in critically ill patients are not well defined in different patient population and ICU settings. Alongside the international guidelines, reaching regional and local consensus on diagnosis and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012669
PubMed Central
by Herrmann, Ken; Buck, Andreas K.; Schuster, Tibor; Abbrederis, Kathrin; Blumel, Christina; Santi, Ivan; Rudelius, Martina; Wester, Hans-Jurgen; Peschel, Christian; Schwaiger, Markus; Dechow, Tobias; Keller, Ulrich
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This article is from Oncotarget , volume 5 . Abstract Despite improved survival in the Rituximab (R) era, a considerable number of patients with diffuse large B-cell lymphoma (DLBCL) ultimately die from the disease. Functional imaging using [18F]fluorodeoxyglucose-PET is suggested for assessment of residual viable tumor very early during treatment but is compromised by non-specific tracer retention in inflammatory lesions. The PET tracer [18F]fluorodeoxythymidine (FLT) as surrogate marker of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147305
PubMed Central
by Tantawy, Mohamed A.; Hatesuer, Bastian; Wilk, Esther; Dengler, Leonie; Kasnitz, Nadine; Weiss, Siegfried; Schughart, Klaus
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This article is from PLoS ONE , volume 9 . Abstract Interferons represent one of the first and essential host defense mechanisms after infection, and the activation of the IFN-pathway results in the transcriptional activation of hundreds of interferon-stimulated genes. The alpha-inducible protein 27 like 2A (Ifi27l2a) gene (human synonym: ISG12) is strongly up-regulated in the lung after influenza A infection in mice and has been shown in gene expression studies to be highly correlated to other...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153650
PubMed Central
by Villaverde, Antonio
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This article is from Microbial Cell Factories , volume 12 . Abstract Contributing reviewers: The Editors of Microbial Cell Factories would like to thank all our Reviewers who have contributed to the journal in Volume 11 (2012).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576239
PubMed Central
by Ferguson, Lydia; Agoulnik, Alexander I.
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eye 146
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This article is from Frontiers in Endocrinology , volume 4 . Abstract The failure of testicular descent or cryptorchidism is the most common defect in newborn boys. The descent of the testes during development is controlled by insulin-like 3 peptide and steroid hormones produced in testicular Leydig cells, as well as by various genetic and developmental factors. While in some cases the association with genetic abnormalities and environmental causes has been shown, the etiology of cryptorchidism...
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Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602796
PubMed Central
by Wallis, M G; Clements, K; Kearins, O; Ball, G; Macartney, J; Lawrence, G M
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This article is from British Journal of Cancer , volume 106 . Abstract Background:: The incidence of ductal carcinoma in situ (DCIS) rose rapidly when the NHS Breast Screening Programme (NHSBSP) started in 1988. Some authorities consider that this represents both over-diagnosis and over-treatment. We report long-term follow-up of DCIS diagnosed in the first 10 years (April 1988 to March 1999) of the West Midlands NHSBSP. Methods:: 840 noninvasive breast cancers were recorded on the national...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349181
PubMed Central
by Muller, Marcel A.; Raj, V. Stalin; Muth, Doreen; Meyer, Benjamin; Kallies, Stephan; Smits, Saskia L.; Wollny, Robert; Bestebroer, Theo M.; Specht, Sabine; Suliman, Tasnim; Zimmermann, Katrin; Binger, Tabea; Eckerle, Isabella; Tschapka, Marco; Zaki, Ali M.; Osterhaus, Albert D. M. E.; Fouchier, Ron A. M.; Haagmans, Bart L.; Drosten, Christian
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This article is from mBio , volume 3 . Abstract A new human coronavirus (hCoV-EMC) has emerged very recently in the Middle East. The clinical presentation resembled that of the severe acute respiratory syndrome (SARS) as encountered during the epidemic in 2002/2003. In both cases, acute renal failure was observed in humans. HCoV-EMC is a member of the same virus genus as SARS-CoV but constitutes a sister species. Here we investigated whether it might utilize angiotensin-converting enzyme 2...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520110
PubMed Central
by Zafar, Morvarid; Iravani, Maryam; Eghbal, Mohammad Jafar; Asgary, Saeed
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This article is from Iranian Endodontic Journal , volume 4 . Abstract INTRODUCTION: This in vitro study aims to evaluate the coronal and apical sealing ability of gutta-percha (GP) root filling used with either mineral trioxide aggregate (MTA), new endodontic cement (NEC) or AH26 as filler/sealers.MATERIALS AND METHODS: Forty eight single-rooted extracted teeth were selected, decoronated and then instrumented. Samples were randomly divided into three experimental (n=12) and two control groups...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712263
PubMed Central
by van Wilgenburg, Bonnie; Moore, Michael D.; James, William S.; Cowley, Sally A.
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This article is from PLoS ONE , volume 9 . Abstract Macrophages constitute an important reservoir of HIV-1 infection, yet HIV-1 entry into these cells is poorly understood due to the difficulty in genetically manipulating primary macrophages. We developed an effective genetic approach to manipulate the sub-cellular distribution of CD4 in macrophages, and investigated how this affects the HIV-1 entry pathway. Pluripotent Stem Cells (PSC) were transduced with lentiviral vectors designed to...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899108
PubMed Central
by Harold, Simon
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eye 236
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This article is from BMC Genetics , volume 15 . Abstract Contributing reviewers: The editors of BMC Genetics would like to thank all of our reviewers who have contributed to the journal in Volume 14 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984743
PubMed Central
by Abou Chakra, Claire Nour; Pepin, Jacques; Sirard, Stephanie; Valiquette, Louis
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This article is from PLoS ONE , volume 9 . Abstract Background: Clostridium difficile infection (CDI) can lead to complications, recurrence, and death. Numerous studies have assessed risk factors for these unfavourable outcomes, but systematic reviews or meta-analyses published so far were limited in scope or in quality. Methods: A systematic review was completed according to PRISMA guidelines. An electronic search in five databases was performed. Studies published until October 2013 were...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045753
PubMed Central
by Stahel, Philip F; Clavien, Pierre-Alain
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eye 263
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This article is from Patient Safety in Surgery , volume 8 . Abstract Contributing reviewers: The Editors of Patient Safety in Surgery would like to thank all our reviewers who have contributed to the journal in Volume 7 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120970
PubMed Central
by Chubiz, Lon M; Purswani, Jessica; Carroll, Sean Michael; Marx, Chistopher J
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This article is from BMC Research Notes , volume 6 . Abstract Background: Due to the ever increasing use of diverse microbial taxa in basic research and industrial settings, there is a growing need for genetic tools to alter the physiology of these organisms. In particular, there is a dearth of inducible expression systems available for bacteria outside commonly used γ-proteobacteria, such as Escherichia coli or Pseudomonas species. To this end, we have sought to develop a pair of inducible...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694467